03/21/2025

Developing Faster, Simpler Tools To Treat Tuberculosis

A woman smiling at the camera.
Mireille Kamariza. Credit: UCLA Samueli School of Engineering

As the United States retreats from global health leadership—withdrawing from the World Health Organization, dismantling USAID—public health experts warn that there will be implications for the spread of certain diseases around the globe. One such disease is tuberculosis (TB), which is the deadliest infectious disease in the world.

If you live in the United States, it’s likely that TB is not on your radar: It’s rare, and if someone is infected, there are effective treatments. But elsewhere in the world, more than a million people die of the bacterium each year, mostly in low-resource, high population regions.

Tuberculosis isn’t a straightforward bug to treat. It has a unique armor, which helps it evade treatment like antibiotics. The current treatment regimen involves taking 16 pills a day for six months, which for people in regions with limited access to medicine, can be a massive barrier.

Joining Host Flora Lichtman to discuss the science behind this deadly bacterium, and new tools to test for and treat it, is Dr. Mireille Kamariza, a chemical biologist at the University of California, Los Angeles.


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Segment Guests

Mireille Kamariza

Dr. Mireille Kamariza is an assistant professor of Bioengineering at UCLA in Los Angeles, California.

Segment Transcript

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About Kathleen Davis

Kathleen Davis is a producer and fill-in host at Science Friday, which means she spends her weeks researching, writing, editing, and sometimes talking into a microphone. She’s always eager to talk about freshwater lakes and Coney Island diners.

About Flora Lichtman

Flora Lichtman is a host of Science Friday. In a previous life, she lived on a research ship where apertivi were served on the top deck, hoisted there via pulley by the ship’s chef.

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