02/14/2025

What Happens To Your Body When You’re Grieving

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We have lots of expressions to describe the pain of loss—heartache, a broken heart, a punch in the gut. These aren’t just figures of speech: While grief is an emotional experience, it’s also a physical one. Studies show that grief can change your physiology, most dramatically in the cardiovascular and immune systems.

One staggering finding? A heart attack is 21 times more likely to happen in the 24 hours after the death of a loved one. And after the death of a parent, risk of ischemic heart disease rises by 41%, and risk of stroke increases by 30%.

Dr. Mary-Frances O’Connor has dedicated her career to understanding the physiology behind grief and grieving. She joins Host Flora Lichtman to discuss what she’s learned over the years, and her new book The Grieving Body.

Read an excerpt of The Grieving Body: How the Stress of Loss Can Be an Opportunity for Healing.


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Segment Guests

Mary-Frances O’Connor

Mary-Frances O’Connor is a neuroscientist and author of The Grieving Body and The Grieving Brain. She’s based in Tucson, Arizona.

Segment Transcript

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About Kathleen Davis

Kathleen Davis is a producer and fill-in host at Science Friday, which means she spends her weeks researching, writing, editing, and sometimes talking into a microphone. She’s always eager to talk about freshwater lakes and Coney Island diners.

About Flora Lichtman

Flora Lichtman is a host of Science Friday. In a previous life, she lived on a research ship where apertivi were served on the top deck, hoisted there via pulley by the ship’s chef.

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