02/14/2025

The FDA Approves A New, Non-Opioid Painkiller

A pill bottle with a blue pill to the right. The bottle's label says "Journavx"
Credit: Business Wire

In January, the Food and Drug Administration approved a new pain medicine called Journavx (suzetrigine), made by Vertex Pharmaceuticals. It’s the first time in 25 years the agency has given the green light to a new painkiller. Notably, it’s not an opioid and, according to the company, it’s not addictive. Unlike opioids, which act directly on the brain, Journavx instead blocks nerve endings across the body that transmit pain.

Host Ira Flatow is joined by Dr. Sean Mackey, a professor of anaesthesiology and pain medicine at Stanford University and chief of the Division of Stanford Pain Medicine, to discuss how the new drug works, who should take it, and what its limitations are.


Further Reading

  • Read more about Journavx via its manufacturer, Vertex Pharmaceuticals.

Donate To Science Friday

Invest in quality science journalism by making a donation to Science Friday.

Donate

Segment Guests

Sean Mackey

Dr. Sean Mackey is a professor of anesthesiology and pain medicine and Chief of the Division of Stanford Pain Medicine at Stanford University in Stanford, California.

Segment Transcript

The transcript of this segment is being processed. It will be available early next week.

Meet the Producers and Host

About D Peterschmidt

D Peterschmidt is a producer, host of the podcast Universe of Art, and composes music for Science Friday’s podcasts. Their D&D character is a clumsy bard named Chip Chap Chopman.

About Ira Flatow

Ira Flatow is the founder and host of Science FridayHis green thumb has revived many an office plant at death’s door.

Explore More