02/07/2025

Investigating Fraud At The Heart Of Alzheimer’s Research

Doctor examining MRI images of patient with multiple sclerosis at table in clinic, closeup
Credit: Shutterstock

Every year, billions of dollars are funneled into Alzheimer’s research. And yet, so far, there’s no treatment that’s been able to reverse the disease, or even meaningfully slow the cognitive decline of patients.

Part of the reason is that the disease is complex, and brain disorders are notoriously difficult to understand.

But in a new book, an investigative science reporter makes the case that there’s another reason progress toward Alzheimer’s treatments has stalled: scientific fraud.

Host Flora Lichtman talks with Charles Piller, investigative journalist at Science and author of the book Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s.

Read an excerpt of Doctored.


Further Reading


Sign Up For The SciFri Book Club Newsletter

Join the SciFri Book Club email newsletter! We send emails a few times per week. If you want to learn more about what we’re reading, you can check out our official Book Club page.

Subscribe

Segment Guests

Charles Piller

Charles Piller is an investigative journalist with Science Magazine in Oakland, California and the author of Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s.

Segment Transcript

The transcript of this segment is being processed. It will be available early next week.

Meet the Producers and Host

About Shoshannah Buxbaum

Shoshannah Buxbaum is a producer for Science Friday. She’s particularly drawn to stories about health, psychology, and the environment. She’s a proud New Jersey native and will happily share her opinions on why the state is deserving of a little more love.

About Flora Lichtman

Flora Lichtman is a host of Science Friday. In a previous life, she lived on a research ship where apertivi were served on the top deck, hoisted there via pulley by the ship’s chef.

Explore More