3,000 Types Of Brain Cells Categorized In Massive Brain Cell Atlas
19:49 minutes
In October 2023, an international group of scientists released an impressively detailed cell atlas of the human brain, published in 21 papers in the journals Science, Science Advances and Science Translational Medicine.
The human brain has roughly 171 billion cells, which makes it a herculean task to categorize them all. Scientists collected samples from different parts of the brain and have identified 3,000 different types of cells. Each cell contains thousands of genes and each cell type only expresses a small fraction of those. Cataloging cells by their gene expressions, paves the way for scientists to tailor disease treatments to target only the affected cells. This human brain cell atlas is only the first draft, but it could signal a paradigm shift in how we understand and treat neurological diseases.
Ira talks with one of the researchers who helped put together the cell atlas, Dr. Ed Lein, senior investigator at the Allen Institute for Brain Science, and takes listener calls.
Dr. Ed Lein is a senior investigator in the Allen Institute for Brain Science in Seattle, Washington.
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Shoshannah Buxbaum is a producer for Science Friday. She’s particularly drawn to stories about health, psychology, and the environment. She’s a proud New Jersey native and will happily share her opinions on why the state is deserving of a little more love.
Ira Flatow is the host and executive producer of Science Friday. His green thumb has revived many an office plant at death’s door.